Duration : 0:2:19

Technorati Tags: bladder, control, Disorders, incontinence, problems, Serels, urinary, voiding

* Watch the outpatient procedure that is restoring quality of life for men with urinary incontinence
* Hear from local patients about their experiences with the Male Sling
* Email your questions for a Live Webcast Response from Dr. McCammon and Dr. Given

Using a recent pre-recorded surgery*, Dr. McCammon, an international leader in the continuing development of the AdVance™ Male Sling, will focus on discussing the procedure that uses three small incisions to implant a mesh sling that supports the urethra and stops urine leakage.

Duration : 0:3:14

Technorati Tags: Advance, bladder, control, incontinence, Male, Sentara, sling, urinary, Urology

Duration : 0:3:7

Technorati Tags: anion, glaucoma, incontinence, ion, Multiple, negative, stroke, testimony, urinary

For more about urogynecology services at Duke, visit http://www.dukehealth.org/Services/Gynecology/Programs/Urogynecology

Duration : 1:1:24

Technorati Tags: duke, incontinence, medicine, urinary, Urogynecology

Duration : 0:5:44

Technorati Tags: acticuf, diapers, incontinence, incontinent, leakage, Male, pads, products, urinary, Urine

“Urinary incontinence is a major problem for women, and for an increasing number of men,” said Ferdinand Frauscher, M.D., associate professor of radiology at the Medical University of Innsbruck and the head of uroradiology at University Hospital. “We believe we have developed a long-lasting and effective treatment that is especially promising because it is generated from the patient’s own body.”

The stem cells are removed from a patient’s arm, cultured in a lab for six weeks, and then injected into the wall of the urethra and into the sphincter muscle. The result is increased muscle mass and contractility of the sphincter and a thicker urethra. Many patients have no urinary leakage within 24 hours after the 15- to 20-minute outpatient procedure.

Stress incontinence affects nearly 15 million people — primarily women — around the world. It occurs when the urethra narrows or becomes otherwise abnormal, or when the sphincter muscles that help open and close the urethra become weak or diminished, causing urine leakage when an individual exercises, coughs, sneezes, laughs or lifts heavy objects.

Twenty females, ages 36 to 84, who were experiencing minor to severe stress incontinence participated in the research. Muscle-derived stem cells were removed from each patient’s arm and cultured, or grown, using a patented technique that yielded 50 million new muscle cells (myoblasts) and 50 million connective tissue cells (fibroblasts) after six weeks. When implanted into the patient under general or local anesthetia, the new stem cells began to replicate the existing cells nearby. One year after the procedure, 18 of the study’s 20 patients remain continent.

“These are very intelligent cells,” Dr. Frauscher said. “Not only do they stay where they are injected, but also they quickly form new muscle tissue and when the muscle mass reaches the appropriate size, the cell growth ceases automatically.”

Since the stem cells must be in contact with urethra and sphincter tissue for the procedure to work, a major factor in the success of this treatment was the development of transurethral three-dimensional ultrasound. “With real-time ultrasound, we are able to see exactly where the new cells must be placed,” Dr. Frauscher said.

Stem cells are unspecialized cells capable of renewing themselves through cell division. Scientists believe that adult stem cells are located in small numbers throughout the tissues of the human body, where they quietly reside until activated by disease or injury and begin dividing. In addition to repairing body tissue, stem cells can be induced to become cells for specialized functions of the body.

Dr. Frauscher said the cost of the stem cell procedure was comparable to two popular treatments for incontinence: the long-term purchase and use of absorbents, such as adult diapers, and collagen injections, which show improvement during the first six months but often result in symptoms returning after a year. Dr. Frauscher also said the stem cell treatment appears to be more successful with women at this time. For men, incontinence is often caused by prostate surgery, which may result in scar tissue formation, where the stem cells do not grow very well. In men without scar tissue stem cell therapy seems to work as well as in women, Dr. Frauscher said.

Duration : 0:0:18

Technorati Tags: incontinence, medicine, returninghope, stress, urinary

Duration : 0:5:55

Technorati Tags: incontinence, Overflow, stress, urinary

Duration : 0:9:17

Technorati Tags: aaron, ambulatory, ams, apogee, bahn, bladder, cohen, cystocele, diary, duke, enterocele, Female, gary, hogdon, incontinence, jeffrey, katz, miniarc, mri, onik, perogee, prolapse, radge, raz, rectocele, Riemenschneider, stress, surgery, urethrocele, urgency, urinary, vaginitis, voiding

Duration : 0:3:6

Technorati Tags: Atty, Center, Detroit, DMC, Grace, hospital, incontinence, Korial, M.D., medical, Sinai, urinary

Duration : 0:1:44

Technorati Tags: bladder, control, find, flotrol, formulas, herbal, incontinence, treatment, urinary, Your